SCHEMBL14640982

SCHEMBL14640982

Cc1cc(F)c2[nH]c3c(c2c1)CCc1cc(C(=O)O)c(O)cc1-3

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MPL P40238 19/20 0.60
NOTUM Q6P988 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102033 0.92 MPL (0.70) MPL
SCHEMBL1102221 0.87 MPL (0.59) MPL
SCHEMBL1102098 0.87 MPL (0.59) MPL
SCHEMBL1102090 0.85 MPL (0.73) MPL
SCHEMBL1092020 0.84 MPL (0.56) MPL
SCHEMBL1102101 0.83 MPL (0.75) MPL
SCHEMBL1102214 0.82 MPL (0.66) MPL
SCHEMBL1102177 0.81 MPL (0.68) MPL
SCHEMBL1091665 0.81 MPL (0.55) MPL
SCHEMBL1102226 0.80 MPL (0.73) MPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007009120-A2 HETEROTETRACYCLIC COMPOUNDS AS TPO MIMETICS IRM LLC (BM) 2007-01-18 WO disclosed