Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.57 |
| ▸ | USP1 | O94782 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14641560 | 0.86 | MET (0.50) | METUSP1 | |
| SCHEMBL14641768 | 0.81 | MET (0.49) | METUSP1FAAH | |
| SCHEMBL14641766 | 0.81 | MET (0.51) | METUSP1FAAH | |
| SCHEMBL12241162 | 0.76 | MET (0.58) | MET | |
| SCHEMBL3087196 | 0.74 | MET (0.85) | MET | |
| SCHEMBL12241201 | 0.74 | MET (0.57) | METTLR7 | |
| SCHEMBL12241187 | 0.74 | MET (0.57) | METTLR7 | |
| SCHEMBL15738436 | 0.73 | MET (0.74) | MET | |
| SCHEMBL3099598 | 0.73 | MET (0.87) | MET | |
| SCHEMBL3765612 | 0.73 | MET (0.67) | METTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150551-B1 | 2-OXO-3-BENZYL-BENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMORS | MERCK PATENT GMBH (DE) | 2013-01-16 | — | — | EP | disclosed |