Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674225 | 0.75 | DYRK1A (0.53) | DYRK1AAHRCD38TNFRIPK1 | |
| SCHEMBL4838531 | 0.72 | DYRK1A (0.41) | DYRK1AAHRTNFRIPK1 | |
| SCHEMBL12804489 | 0.72 | DYRK1A (0.41) | DYRK1AAHRCD38TNFRIPK1 | |
| SCHEMBL4838737 | 0.72 | DYRK1A (0.41) | DYRK1AAHRCD38TNFRIPK1 | |
| SCHEMBL14620622 | 0.68 | XDH (0.51) | — | |
| SCHEMBL18194341 | 0.68 | XDH (0.51) | DYRK1AAHRCD38 | |
| SCHEMBL29495204 | 0.67 | CD38 (0.39) | DYRK1ACD38 | |
| SCHEMBL31230009 | 0.66 | MAPK1 (0.41) | DYRK1A | |
| SCHEMBL22754157 | 0.64 | JAK2 (0.46) | AHR | |
| SCHEMBL23098929 | 0.62 | KDM4E (0.41) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354408-B2 | N-containing heterocyclic compounds | YM BIOSCIENCES AUSTRALIA PTY LTD (AU) | 2013-01-15 | — | — | US | disclosed |