Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12520821 | 0.84 | CYP11B1 (0.59) | CYP1A2CYP2A6CYP11B1ALDH1A1HSD17B10 | |
| SCHEMBL16407360 | 0.83 | CYP11B1 (0.47) | CYP1A2CYP2A6CYP11B1ALDH1A1HPGD | |
| SCHEMBL24174147 | 0.82 | GPR84 (0.53) | CYP1A2CYP2A6CYP11B1ALDH1A1HSD17B10 | |
| SCHEMBL14297104 | 0.81 | CYP11B1 (0.39) | CYP1A2CYP2A6CYP11B1BRD9BRD7 | |
| SCHEMBL4546821 | 0.81 | KDM4E (0.41) | CYP1A2CYP2A6CYP11B1BRD9BRD7 | |
| SCHEMBL18575590 | 0.80 | GPR84 (0.44) | CYP1A2CYP2A6CYP11B1BRD9BRD7 | |
| SCHEMBL19998856 | 0.79 | CYP11B1 (0.41) | CYP1A2CYP2A6CYP11B1ALDH1A1HPGD | |
| SCHEMBL19998838 | 0.79 | CYP11B1 (0.41) | CYP1A2CYP2A6CYP11B1ALDH1A1HPGD | |
| SCHEMBL20081061 | 0.79 | CYP11B1 (0.72) | CYP1A2CYP2A6CYP11B1ALDH1A1HPGD | |
| SCHEMBL19998860 | 0.79 | CYP11B1 (0.41) | CYP1A2CYP2A6CYP11B1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354515-B2 | Oligonucleotide derivative, labeling agent and use for labeling agent | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-01-15 | — | — | US | disclosed |