SCHEMBL1464252

SCHEMBL1464252

c1csc2cccc-2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27709556 0.97 CYP3A4 (0.60)
SCHEMBL31124 0.94 CYP3A4 (0.58)
SCHEMBL338810 0.94 LTA4H (0.70)
Hydrochloric Acid SCHEMBL27688178 0.92 CYP3A4 (0.56)
SCHEMBL1334921 0.92 KCNH2 (0.59)
Hydrogen Sulfide SCHEMBL27668457 0.92 CYP3A4 (0.56)
Ammonia Solution, Strong SCHEMBL28465317 0.92 CYP3A4 (0.56)
SCHEMBL30163538 0.92 CYP3A4 (0.56)
Hydrochloric Acid SCHEMBL8091091 0.92 CYP3A4 (0.56)
SCHEMBL7455134 0.91 LTA4H (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005605-A Method for synthesizing arylthianthrene onium salt under mechanochemical condition 扬州大学 2024-05-10 CN claimed
CN-115650850-A Nano-oxide surface modifier based on fatty acid and preparation method and application thereof 武汉轻工大学 2023-01-31 CN claimed
CN-105349137-B Electroluminescent material with bipolar carrier transmission performance and the application as organic electroluminescence device material of main part 陕西师范大学 2017-07-11 CN claimed
CN-105753883-A Triphenylamine-benzothiophene organic small-molecule hole transporting material and application thereof 中南大学 2016-07-13 CN claimed
CN-101421257-A Agents that disrupt cellular replication and their use in inhibiting pathological conditions EUROPEAN MOLECULAR BIOLOGY LAB EMBL (DE) 2009-04-29 CN claimed
EP-1764358-A2 Cyclic amides as vanilloid receptor ligands and their use in treatments of inflammatory and neuropathic pain Amgen, Inc (US) 2007-03-21 EP claimed
US-20050272931-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2005-12-08 US claimed
EP-1463714-A4 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS AMGEN INC (US) 2005-10-19 EP claimed
US-20050227986-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2005-10-13 US claimed
EP-1463714-A2 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS Amgen Inc. (US) 2004-10-06 EP claimed
US-20030195201-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2003-10-16 US claimed
WO-2003049702-A2 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS AMGEN INC. (US) 2003-06-19 WO claimed
EP-0466730-B1 GEMINAL BISPHOSPHONIC ACIDS AND DERIVATIVES AS ANTI-ARTHRITIC AGENTS THE UPJOHN COMPANY (US) 1993-07-21 EP claimed
US-5220021-A Geminal bisphosphonic acids and derivatives as anti-arthritic agents THE UPJOHN COMPANY (US) 1993-06-15 US claimed
EP-0466730-A1 GEMINAL BISPHOSPHONIC ACIDS AND DERIVATIVES AS ANTI-ARTHRITIC AGENTS. UPJOHN CO (US) 1992-01-22 EP claimed
WO-1990012017-A1 GEMINAL BISPHOSPHONIC ACIDS AND DERIVATIVES AS ANTI-ARTHRITIC AGENTS THE UPJOHN COMPANY (US) 1990-10-18 WO claimed
CN-115087654-B Material for organic electroluminescent device 默克专利有限公司 2025-03-28 CN disclosed
CN-114755889-B Dry film resist and photosensitive dry film 杭州福斯特电子材料有限公司 2024-12-31 CN disclosed
EP-0466730-A1 GEMINAL BISPHOSPHONIC ACIDS AND DERIVATIVES AS ANTI-ARTHRITIC AGENTS. UPJOHN CO (US) 1992-01-22 EP disclosed
WO-1990012017-A1 GEMINAL BISPHOSPHONIC ACIDS AND DERIVATIVES AS ANTI-ARTHRITIC AGENTS THE UPJOHN COMPANY (US) 1990-10-18 WO disclosed