Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | ADK | P55263 | 6/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | STAT6 | P42226 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16330675 | 0.90 | HIF1A (0.64) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL16330664 | 0.89 | HIF1A (0.61) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL16330766 | 0.88 | HIF1A (0.62) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL16330722 | 0.87 | HIF1A (0.65) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL16330723 | 0.86 | HIF1A (0.63) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL16330767 | 0.84 | HIF1A (0.55) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL16330724 | 0.84 | HIF1A (0.60) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL16330668 | 0.83 | HIF1A (0.66) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL12284106 | 0.82 | HIF1A (0.62) | HIF1APAX8DOT1LPRMT5PRMT3 | |
| SCHEMBL16330754 | 0.81 | HIF1A (0.51) | HIF1APAX8DOT1LPRMT5PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018010-A1 | POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS | ENZON PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018010-A1 | POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS | VEGFA, MKI67, PCNA | HIF1A 922/4885PAX8 3693/4885DOT1L 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.