Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.61 |
| ▸ | WDR77 | Q9BQA1 | 16/20 | 0.61 |
| ▸ | ADK | P55263 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21413841 | 0.91 | PRMT5 (0.72) | PRMT5WDR77ADK | |
| SCHEMBL13134824 | 0.91 | PRMT5 (0.72) | PRMT5WDR77ADK | |
| SCHEMBL19242446 | 0.84 | ADK (0.61) | PRMT5WDR77ADK | |
| SCHEMBL18026164 | 0.84 | PRMT5 (0.83) | PRMT5WDR77 | |
| SCHEMBL18026151 | 0.84 | PRMT5 (0.68) | PRMT5WDR77 | |
| SCHEMBL18026130 | 0.84 | PRMT5 (0.68) | PRMT5WDR77 | |
| SCHEMBL18026040 | 0.84 | PRMT5 (0.83) | PRMT5WDR77 | |
| SCHEMBL12831663 | 0.81 | ADK (0.66) | PRMT5WDR77ADK | |
| SCHEMBL14609525 | 0.81 | ADK (0.66) | PRMT5WDR77ADK | |
| SCHEMBL18026086 | 0.80 | PRMT5 (0.85) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013009735-A1 | 5'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | WO | disclosed |