Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14644383 | 0.81 | TRPV1 (0.70) | TRPV1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL14644389 | 0.79 | PRKCI (0.55) | TRPV1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14644393 | 0.79 | TRPV1 (0.70) | TRPV1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5664372 | 0.78 | RPS6KB2 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20621378 | 0.78 | KDM4E (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6874856 | 0.78 | KDM4E (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16561480 | 0.75 | SMN1; SMN2 (0.60) | HDAC1MAPTGAAALDH1A1 | |
| SCHEMBL15453234 | 0.74 | KDM4E (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5663650 | 0.72 | KDM4E (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6850784 | 0.71 | KDM4E (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013007792-A1 | NOVEL TH2 POLARIZING COMPOUNDS | THURGAUISCHE STIFTUNG FÜR WISSENSCHAFT UND FORSCHUNG (CH) | 2013-01-17 | — | — | WO | disclosed |