Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14644383 | 0.86 | TRPV1 (0.70) | TRPV1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL14644393 | 0.86 | TRPV1 (0.70) | TRPV1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL14644384 | 0.79 | TRPV1 (0.48) | TRPV1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL9634863 | 0.75 | HPGD (0.50) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL18866660 | 0.73 | PRKCI (0.62) | PRKCIHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL20388926 | 0.69 | PRKCI (0.66) | PRKCIHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL8352676 | 0.69 | USP2 (0.57) | TRPV1 | |
| SCHEMBL17203114 | 0.69 | TRPV1 (0.66) | TRPV1HDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL17205531 | 0.69 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL17203122 | 0.69 | TRPV1 (0.65) | TRPV1HDAC1HDAC2HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013007792-A1 | NOVEL TH2 POLARIZING COMPOUNDS | THURGAUISCHE STIFTUNG FÜR WISSENSCHAFT UND FORSCHUNG (CH) | 2013-01-17 | — | — | WO | disclosed |