Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 12/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478403 | 0.89 | KCNA5 (0.63) | KCNA5EGFRUSP2HSD17B10 | |
| SCHEMBL1477870 | 0.88 | KCNA5 (0.72) | KCNA5EGFR | |
| SCHEMBL14644961 | 0.84 | KCNA5 (0.68) | KCNA5EGFR | |
| SCHEMBL1478379 | 0.84 | KCNA5 (0.67) | KCNA5TSHR | |
| SCHEMBL1478669 | 0.84 | KCNA5 (0.67) | KCNA5 | |
| SCHEMBL1480523 | 0.84 | KCNA5 (0.67) | KCNA5 | |
| SCHEMBL1478452 | 0.79 | KCNA5 (0.64) | KCNA5 | |
| SCHEMBL14644960 | 0.79 | KCNA5 (0.58) | KCNA5 | |
| SCHEMBL1480214 | 0.79 | KCNA5 (0.58) | KCNA5 | |
| SCHEMBL1478871 | 0.78 | KCNA5 (1.00) | KCNA5EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357809-B2 | Acyclic IKur inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-22 | — | — | US | disclosed |