Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhodomyrtoxin SCHEMBL12210330 | 0.95 | FBP1 (0.49) | FBP1MEN1LMNATP53MAPT | |
| SCHEMBL504402 | 0.90 | MEN1 (0.55) | FBP1MEN1LMNATP53MAPT | |
| SCHEMBL9752800 | 0.76 | FFAR1 (0.62) | FBP1FFAR1HIF1AEPAS1BCL2L1 | |
| Grandinol SCHEMBL31348060 | 0.67 | FFAR1 (0.47) | FBP1MAPTFFAR1HIF1AEPAS1 | |
| SCHEMBL29287621 | 0.66 | FFAR1 (0.79) | FBP1FFAR1BCL2L1PLA2G2APLA2G5 | |
| SCHEMBL505148 | 0.63 | FBP1 (1.00) | FBP1FFAR1HIF1AEPAS1BCL2L1 | |
| Rhodomyrtoxin B SCHEMBL12827333 | 0.62 | MAPT (1.00) | FBP1MEN1LMNATP53MAPT | |
| SCHEMBL29664009 | 0.61 | CYP3A4 (0.61) | MEN1MAPTKMT2AFFAR1 | |
| SCHEMBL7887580 | 0.61 | FFAR1 (0.85) | FBP1FFAR1BCL2L1PLA2G2APLA2G5 | |
| SCHEMBL11422414 | 0.61 | FFAR1 (0.43) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357701-B2 | Galactokinase inhibitors | UNIVERSITY OF MIAMI (US) | 2013-01-22 | — | — | US | disclosed |