Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | GBA1 | P04062 | 3/20 | 0.54 |
| ▸ | GLB1 | P16278 | 3/20 | 0.54 |
| ▸ | EDNRA | P25101 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139459 | 0.88 | HDAC4 (0.75) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL4126957 | 0.88 | HDAC4 (0.71) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL4142506 | 0.87 | HDAC4 (0.77) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL13598768 | 0.85 | HDAC4 (0.59) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL10002024 | 0.84 | HDAC4 (0.67) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL23964395 | 0.83 | HDAC4 (0.69) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL12502117 | 0.83 | HDAC4 (0.65) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL4782146 | 0.83 | HDAC4 (0.69) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL29376225 | 0.83 | HDAC4 (0.69) | HDAC4HDAC10HDAC6HDAC5GBA1 | |
| SCHEMBL8488157 | 0.83 | HDAC4 (0.65) | HDAC4HDAC10HDAC6HDAC5GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357532-B2 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-01-22 | — | — | US | disclosed |