SCHEMBL14645562

SCHEMBL14645562

Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)c(O)cc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 5/20 0.63
ALDH1A1 P00352 2/20 0.63
HSD17B10 Q99714 2/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
NT5E P21589 3/20 0.56
NSD2 O96028 4/20 0.51
DUSP3 P51452 2/20 0.51
PTPN5 P54829 2/20 0.51
PTPN11 Q06124 2/20 0.51
GAA P10253 1/20 0.45
PLCG1 P19174 1/20 0.45
DNMT1 P26358 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP1A2 P05177 1/20 0.42
ENPP2 Q13822 2/20 0.41
PRMT1 Q99873 2/20 0.41
AURKA O14965 1/20 0.41
AURKB Q96GD4 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8863515 0.88 CASP6 (0.69) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL31635711 0.84 NT5E (0.60) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL2989602 0.84 CASP6 (0.47) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL31615025 0.84 CASP6 (0.47) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL7798817 0.84 NT5E (0.60) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
Potassium SCHEMBL11226227 0.83 NT5E (0.58) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL3502679 0.83 CASP6 (0.46) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL11137556 0.83 CASP6 (0.67) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL11226223 0.83 NT5E (0.58) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL943858 0.80 NT5E (0.64) CASP6ALDH1A1HSD17B10CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013008201-A2 NOVEL REACTIVE DYES, THERE MIXTURES AND PROCESSES THEREOF COLOURTEX INDUSTRIES LIMITED (IN) 2013-01-17 WO disclosed