Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3048108 | 0.79 | CYP1A2 (0.41) | HPGD | |
| SCHEMBL3046028 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL2573293 | 0.78 | APP (0.34) | DAOPTGS1CNR2POLBHPGD | |
| SCHEMBL12990116 | 0.78 | KAT8 (0.35) | DAOKAT8 | |
| SCHEMBL4940256 | 0.77 | KCNH2 (0.34) | CNR1CNR2 | |
| SCHEMBL3981104 | 0.77 | CYP1A2 (0.44) | HPGD | |
| SCHEMBL17900495 | 0.76 | KDM4E (0.30) | — | |
| SCHEMBL12385817 | 0.76 | KDM4E (0.30) | — | |
| SCHEMBL12824347 | 0.75 | CNR2 (0.32) | DAOCNR1CNR2 | |
| SCHEMBL2226265 | 0.74 | SMYD3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342200-B1 | Compounds which selectively modulate the cb2 receptor | BOEHRINGER INGELHEIM INT (DE) | 2013-01-23 | — | — | EP | disclosed |