Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698521 | 0.93 | MGLL (1.00) | MGLLFAAH | |
| SCHEMBL14647981 | 0.92 | MGLL (0.83) | MGLLFAAH | |
| SCHEMBL697821 | 0.90 | MGLL (0.85) | MGLLFAAH | |
| SCHEMBL14647893 | 0.90 | MGLL (0.84) | MGLLFAAH | |
| SCHEMBL911461 | 0.89 | MGLL (0.81) | MGLLFAAH | |
| SCHEMBL911357 | 0.88 | MGLL (0.85) | MGLLFAAH | |
| SCHEMBL910669 | 0.88 | MGLL (0.85) | MGLLFAAH | |
| SCHEMBL912325 | 0.88 | MGLL (0.84) | MGLLFAAH | |
| SCHEMBL14827113 | 0.88 | MGLL (0.84) | MGLLFAAH | |
| SCHEMBL14647931 | 0.88 | MGLL (0.79) | MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421823-B1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-01-14 | — | — | EP | disclosed |
| EP-2421825-B9 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-20 | — | — | EP | disclosed |
| EP-2421825-B1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-01-01 | — | — | EP | disclosed |
| US-8362000-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-29 | — | — | US | disclosed |