SCHEMBL14650100

SCHEMBL14650100

c1ccc2cc(-c3c4ccccc4c(-c4ccc(-n5c6ccc7ccccc7c6c6c7ccccc7ccc65)cc4)c4ccccc34)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.35
ESR2 Q92731 3/20 0.35
GSTP1 P09211 1/20 0.35
ALOX5 P09917 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
PDE9A O76083 1/20 0.35
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NQO2 P16083 1/20 0.34
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GPR84 Q9NQS5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19296520 0.94 PIK3CD (0.37) ESR1ESR2GSTP1ALOX5CYP1A1
SCHEMBL19296518 0.92 PIK3CD (0.35) ESR1ESR2GSTP1ALOX5CYP1A1
SCHEMBL19296525 0.92 PIK3CD (0.35) ESR1ESR2GSTP1ALOX5CYP1A1
SCHEMBL19296516 0.92 ALOX5 (0.39) ESR1ESR2GSTP1ALOX5CYP1A1
SCHEMBL19296552 0.92 PIK3CD (0.35) ESR1ESR2ALOX5CYP1A1CYP1B1
SCHEMBL19296515 0.91 ESR1 (0.37) ESR1ESR2ALOX5CYP1A1CYP1B1
SCHEMBL22483176 0.91 ESR1 (0.44) ESR1ESR2GSTP1ALOX5CYP1A1
SCHEMBL29373896 0.91 KDM4E (0.40) ESR1ESR2ALOX5CYP1A1KDM4E
SCHEMBL14632626 0.91 KDM4E (0.40) ESR1ESR2ALOX5CYP1A1KDM4E
SCHEMBL19296526 0.90 ALOX5 (0.34) ESR1ESR2ALOX5CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9537109-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-01-03 US disclosed
US-20160233437-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-11 US disclosed
US-20160233437-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-11 US disclosed
US-9257655-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-02-09 US disclosed
US-9240558-B2 Dibenzole[c,g]carbazole compound, light-emitting element, light-emitting device, display device, lighting device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-01-19 US disclosed
US-9240558-B2 Dibenzole[c,g]carbazole compound, light-emitting element, light-emitting device, display device, lighting device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-01-19 US disclosed
US-20150171347-A1 Dibenzole[c,g]Carbazole Compound, Light-Emitting Element, Light-Emitting Device, Display Device, Lighting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171347-A1 Dibenzole[c,g]Carbazole Compound, Light-Emitting Element, Light-Emitting Device, Display Device, Lighting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8986857-B2 Dibenzo[c,g]carbazole compound, light-emitting element, light-emitting device, display device, lighting device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-24 US disclosed
US-8986857-B2 Dibenzo[c,g]carbazole compound, light-emitting element, light-emitting device, display device, lighting device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-24 US disclosed
US-20140159011-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-06-12 US disclosed
US-20140159011-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-06-12 US disclosed
WO-2013015144-A1 DIBENZO[c,g]CARBAZOLE COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, DISPLAY DEVICE, LIGHTING DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-31 WO disclosed
US-20130020561-A1 Dibenzo[c,g]Carbazole Compound, Light-Emitting Element, Light-Emitting Device, Display Device, Lighting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-01-24 US disclosed
US-20130020561-A1 Dibenzo[c,g]Carbazole Compound, Light-Emitting Element, Light-Emitting Device, Display Device, Lighting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150171347-A1 Dibenzole[c,g]Carbazole Compound, Light-Emitting Element, Light-Emitting Device, Display Device, Lighting Device and Electronic Device CDA, APOBEC3G, BRD9 ESR1 565/4885ESR2 1205/4885GSTP1 921/4885
US-20130020561-A1 Dibenzo[c,g]Carbazole Compound, Light-Emitting Element, Light-Emitting Device, Display Device, Lighting Device and Electronic Device APOBEC3G, CDA, DRD1 ESR1 617/4885ESR2 1333/4885GSTP1 902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.