Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650627 | 0.92 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650677 | 0.88 | KMT2A (0.38) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650721 | 0.83 | KMT2A (0.34) | RAB9ASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL14650706 | 0.82 | MCHR1 (0.37) | RAB9ASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL14650555 | 0.81 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650694 | 0.79 | POLB (0.43) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| SCHEMBL14268831 | 0.79 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650697 | 0.78 | ESR1 (0.32) | KMT2A | |
| SCHEMBL14650634 | 0.78 | TDP1 (0.43) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650718 | 0.77 | CA12 (0.35) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |