Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650728 | 0.92 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650555 | 0.86 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14268831 | 0.84 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650634 | 0.83 | TDP1 (0.43) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650703 | 0.80 | TDP1 (0.41) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL5530144 | 0.79 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650638 | 0.77 | PDE6D (0.41) | SMN1; SMN2HTTMEN1KMT2AKDM4E | |
| SCHEMBL14650677 | 0.77 | KMT2A (0.38) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL14650653 | 0.75 | MGLL (0.43) | SMN1; SMN2LMNAHTTMEN1KMT2A | |
| SCHEMBL5021832 | 0.75 | MEN1 (0.56) | NPC1RAB9ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |