SCHEMBL1465422

SCHEMBL1465422

CCCCOC(=O)N1CCCC(C(=O)Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)C1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1465512 0.90 CCNT1 (0.74) CCNT1
SCHEMBL1947213 0.90 CCNT1 (0.74) CCNT1
SCHEMBL1465429 0.90 CCNT1 (0.74) CCNT1
SCHEMBL12501652 0.88 CDK9 (0.43) CCNT1
SCHEMBL1464265 0.84 CCNT1 (0.75) CCNT1
SCHEMBL1462932 0.78 CCNT1 (0.73) CCNT1
SCHEMBL1463044 0.78 CCNT1 (0.73) CCNT1
SCHEMBL1944753 0.77 CCNT1 (0.54) CCNT1
SCHEMBL1944749 0.77 CCNT1 (0.54) CCNT1
SCHEMBL1462840 0.77 CCNT1 (0.57) CCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2473499-A1 BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES Novartis AG (CH) 2012-07-11 EP disclosed
WO-2011026911-A1 BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES NOVARTIS AG (CH) 2011-03-10 WO disclosed