Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GSR | P00390 | 2/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233113 | 1.00 | FOLH1 (0.45) | FOLH1DPP4ARG1CYP19A1CYP1A1 | |
| SCHEMBL14656535 | 0.90 | ARG1 (0.52) | FOLH1DPP4ARG1CYP19A1CYP1A1 | |
| SCHEMBL5499057 | 0.86 | DPP4 (0.44) | FOLH1DPP4ARG1CYP19A1CYP1A1 | |
| SCHEMBL5499917 | 0.86 | DPP4 (0.44) | FOLH1DPP4ARG1CYP19A1CYP1A1 | |
| SCHEMBL5499054 | 0.85 | DPP4 (0.43) | FOLH1DPP4ARG1CYP19A1CYP1A1 | |
| SCHEMBL5499916 | 0.85 | DPP4 (0.43) | FOLH1DPP4ARG1CYP19A1CYP1A1 | |
| SCHEMBL27115174 | 0.85 | DPP4 (0.43) | FOLH1DPP4ARG1CYP19A1CYP1A1 | |
| SCHEMBL6395050 | 0.82 | FOLH1 (0.55) | FOLH1CYP19A1CYP1A1SLC1A3 | |
| SCHEMBL612982 | 0.82 | FOLH1 (0.55) | FOLH1CYP19A1CYP1A1SLC1A3 | |
| SCHEMBL18546548 | 0.76 | PADI4 (0.62) | CYP19A1CYP1A1ALDH1A1SLC1A1PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130029920-A1 | Metal Nanoparticles | BRIMBLE MARGARET A (NZ) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029920-A1 | Metal Nanoparticles | PSTPIP2, PCNP, ANPEP | FOLH1 352/4885DPP4 924/4885ARG1 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.