SCHEMBL146566

SCHEMBL146566

O=S(=O)(c1ccc(Oc2ccccc2)cc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.81
SMN1; SMN2 Q16637 2/20 0.81
SOS1 Q07889 1/20 0.69
LMNA P02545 3/20 0.62
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
HTR6 P50406 1/20 0.59
LTA4H P09960 1/20 0.57
TSHR P16473 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
MMP3 P08254 3/20 0.56
MMP8 P22894 3/20 0.56
MMP13 P45452 2/20 0.56
MMP2 P08253 2/20 0.56
MMP9 P14780 2/20 0.56
MMP14 P50281 2/20 0.56
MMP12 P39900 1/20 0.56
MMP16 P51512 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17559302 1.00 HTT (0.81) HTTSMN1; SMN2SOS1LMNATDP1
SCHEMBL6123058 1.00 HTT (0.81) HTTSMN1; SMN2SOS1LMNATDP1
SCHEMBL11415437 1.00 HTT (0.81) HTTSMN1; SMN2SOS1LMNATDP1
SCHEMBL9323430 0.98 HTT (0.78) HTTSMN1; SMN2SOS1LMNATDP1
SCHEMBL6848913 0.95 HTT (0.74) HTTSMN1; SMN2SOS1LMNATDP1
SCHEMBL9452130 0.94 HTT (0.72) HTTSMN1; SMN2SOS1LMNATDP1
(Phenylsulfonyl)Benzene SCHEMBL2126656 0.93 HTT (0.70) HTTSMN1; SMN2SOS1LMNATDP1
Biphenyl SCHEMBL1071652 0.92 HTT (0.70) HTTSMN1; SMN2SOS1LMNATDP1
SCHEMBL23430824 0.90 LTA4H (0.69) HTTSMN1; SMN2SOS1LMNATDP1
SCHEMBL12643091 0.90 HTT (1.00) HTTSMN1; SMN2SOS1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113174037-B Linear high heat-resistant oxidized polyaryletherketone ketone and preparation method thereof 江阴市博生新材料科技有限公司 2022-05-17 CN claimed
CN-113174037-A Linear high heat-resistant oxidized polyaryletherketone ketone and preparation method thereof 江阴市博生新材料科技有限公司 2021-07-27 CN claimed
EP-0866110-B1 Light-emitting material for organo-electroluminescence device and organic electroluminescence device TOYO INK MFG CO (JP) 2004-10-20 EP claimed
EP-0810476-A1 Polyamic acid esters and positive type photosensitive resin compositions and their use for polyimide films for electronic devices HITACHI CHEMICAL CO., LTD. (JP) 1997-12-03 EP claimed
US-5374469-A Using thermoplastic polyimide resin showing adhesive properties by press bending by heating, using low-linear expansion polyimide NITTO DENKO CORPORATION (JP) 1994-12-20 US claimed
US-5238983-A Heat and oxidation resistance, glass transition temperature, viscosity HUELS AKTIENGESELLSCHAFT (DE) 1993-08-24 US claimed
EP-0533198-A2 Flexible printed substrate NITTO DENKO CORPORATION (JP) 1993-03-24 EP claimed
EP-0498958-A1 Moulding masses based on thermoplastic workable aromatic polyamide HÜLS AKTIENGESELLSCHAFT (DE) 1992-08-19 EP claimed
EP-0388030-A2 Polyarylketones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-09-19 EP claimed
US-4861856-A Process for the preparation of polyketone and poly(ketone-sulfone) polymers EASTMAN KODAK COMPANY (US) 1989-08-29 US claimed
US-4794155-A Process for forming arylether polymers THE DOW CHEMICAL COMPANY (US) 1988-12-27 US claimed
EP-0266497-A1 Wholly aromatic polyester composition and process for producing it TEIJIN LIMITED (JP) 1988-05-11 EP claimed
US-4499258-A HEAT-RESISTANT LAMINATES; FILMS;HIGH STRENGTH THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1985-02-12 US claimed
US-4414380-A IN POLYCARBONYLS UOP INC. (US) 1983-11-08 US claimed
US-4356292-A FROM ACID CHLORIDE OF BIS-M-CARBOXYPHENYLACETYLENE, DIPHENYL ETHER, ISOPHTHALOYL CHLORIDE, 4,4'-DIPHENOXYDIPHENYL SULFONE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1982-10-26 US claimed
US-4228262-A SULFUR COMPOUND ALUMINUM CHLORIDE-TITANIUM CHLORIDE COMPLEX POLYMERIZATION CATALYST IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-10-14 US claimed
US-4161461-A OLEFIN COORDINATION-POLYMERIZATION CATALYST; TRANSITION METAL HALIDE TREATED WITH ORGANIC SULFONE, SULFONAMIDE OR SULFIDE AND GRINDED WITH ALUMINUM AND TITANIUM CHLORIDES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-07-17 US claimed
JP-2004829-A None JP disclosed
US-3983300-A POLYAROMATIC SULFONE IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) 1976-09-28 US disclosed
US-3935167-A Acetylenic polymers, trimers thereof and the production thereof UNIVERSITY PATENTS, INC. (US) 1976-01-27 US disclosed