Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21663431 | 0.67 | KDM4E (0.33) | KDM4EPOLBL3MBTL1 | |
| SCHEMBL31265523 | 0.67 | CA1 (0.37) | CA1CA2CA4KMT2A | |
| SCHEMBL31113358 | 0.67 | — | — | |
| SCHEMBL31113396 | 0.62 | CA1 (0.38) | CA1CA2CA4KMT2A | |
| SCHEMBL8419229 | 0.61 | KMT2A (0.40) | CA1CA2CA4KMT2AALDH1A1 | |
| SCHEMBL21940584 | 0.58 | CA1 (0.33) | CA1CA2CA4KMT2A | |
| SCHEMBL11054767 | 0.57 | KMT2A (0.35) | CA1CA2CA4KMT2ATDP1 | |
| SCHEMBL3926378 | 0.57 | — | — | |
| Bicarbonate SCHEMBL10617200 | 0.56 | — | — | |
| Cyclopentanone SCHEMBL8542126 | 0.56 | TRIM24 (0.71) | KDM4EPOLBL3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140171616-A1 | SELF-ADHESIVE COMPOSITION AND SELF-ADHESIVE FILM FOR GLASS MANUFACTURED THEREFROM | SK GLOBAL CHEMICAL CO., LTD. (KR) | 2014-06-19 | — | — | US | claimed |
| EP-2736997-A1 | SELF-ADHESIVE COMPOSITION AND SELF-ADHESIVE FILM FOR GLASS MANUFACTURED THEREFROM | SK Innovation Co., Ltd. (KR) | 2014-06-04 | — | — | EP | claimed |
| WO-2013015522-A1 | SELF-ADHESIVE COMPOSITION AND SELF-ADHESIVE FILM FOR GLASS MANUFACTURED THEREFROM | SK INNOVATION CO.,LTD. (KR) | 2013-01-31 | — | — | WO | claimed |
| US-9018318-B2 | Catalysts for the preparation of carbonates from epoxides and CO2 | BASF SE Corporation (DE) | 2015-04-28 | — | — | US | disclosed |
| US-20140171616-A1 | SELF-ADHESIVE COMPOSITION AND SELF-ADHESIVE FILM FOR GLASS MANUFACTURED THEREFROM | SK GLOBAL CHEMICAL CO., LTD. (KR) | 2014-06-19 | — | — | US | disclosed |
| EP-2736997-A1 | SELF-ADHESIVE COMPOSITION AND SELF-ADHESIVE FILM FOR GLASS MANUFACTURED THEREFROM | SK Innovation Co., Ltd. (KR) | 2014-06-04 | — | — | EP | disclosed |
| US-20130060001-A1 | CATALYSTS FOR THE PREPARATION OF CARBONATES FROM EPOXIDES AND CO2 | BASF SE (DE) | 2013-03-07 | — | — | US | disclosed |
| WO-2013015522-A1 | SELF-ADHESIVE COMPOSITION AND SELF-ADHESIVE FILM FOR GLASS MANUFACTURED THEREFROM | SK INNOVATION CO.,LTD. (KR) | 2013-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060001-A1 | CATALYSTS FOR THE PREPARATION OF CARBONATES FROM EPOXIDES AND CO2 | TPRKB, PKD1, MCCC2 | KDM4E 218/4885POLB 1366/4885L3MBTL1 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.