Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALB | P02768 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14664272 | 1.00 | LMNA (0.53) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL14664273 | 1.00 | LMNA (0.53) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL5086587 | 0.89 | LMNA (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL6394877 | 0.89 | LMNA (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL13389887 | 0.88 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL13389809 | 0.88 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL3307297 | 0.88 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL13407904 | 0.88 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL13389683 | 0.88 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL14664271 | 0.88 | LMNA (0.51) | LMNAALBBLMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361988-B2 | Nucleoside and nucleotide analogues with quaternary carbon centers and methods of use | INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) | 2013-01-29 | — | — | US | disclosed |