⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685237 | 1.00 | KDM4E (0.39) | — | |
| SCHEMBL4359852 | 1.00 | — | — | |
| SCHEMBL615001 | 1.00 | KDM4E (0.39) | — | |
| SCHEMBL2495557 | 1.00 | — | — | |
| SCHEMBL13444708 | 1.00 | KDM4E (0.39) | — | |
| SCHEMBL24843176 | 1.00 | KDM4E (0.39) | — | |
| SCHEMBL16360071 | 1.00 | KDM4E (0.39) | — | |
| SCHEMBL14424191 | 1.00 | KDM4E (0.39) | — | |
| SCHEMBL15498544 | 1.00 | KDM4E (0.39) | — | |
| SCHEMBL22300612 | 0.91 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140249105-A1 | NOVEL CERAMIDE ANALOGUES, PROCESSES FOR PREPARING SAME AND USES THEREOF | DIVERCHIM (FR) | 2014-09-04 | — | — | US | disclosed |
| US-20140249105-A1 | NOVEL CERAMIDE ANALOGUES, PROCESSES FOR PREPARING SAME AND USES THEREOF | DIVERCHIM (FR) | 2014-09-04 | — | — | US | disclosed |
| WO-2013013505-A1 | 9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUND | 山东亨利医药科技有限责任公司 (CN) | 2013-01-31 | — | — | WO | disclosed |