Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.71 |
| ▸ | PLAU | P00749 | 8/20 | 0.71 |
| ▸ | PLG | P00747 | 6/20 | 0.65 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.65 |
| ▸ | F2 | P00734 | 4/20 | 0.65 |
| ▸ | HPN | P05981 | 1/20 | 0.58 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.58 |
| ▸ | PLAT | P00750 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14669448 | 0.92 | F10 (0.70) | F10PLAUPLGST14F2 | |
| SCHEMBL14669330 | 0.89 | F10 (0.88) | F10PLAUPLGST14F2 | |
| SCHEMBL14669329 | 0.81 | F10 (0.87) | F10PLAUPLGST14F2 | |
| SCHEMBL14669450 | 0.80 | F10 (0.74) | F10PLAUPLGST14F2 | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL7137671 | 0.77 | PLAU (0.65) | F10PLAUPLGST14F2 | |
| SCHEMBL14669460 | 0.77 | PLG (0.84) | F10PLAUPLGHPN | |
| SCHEMBL14669328 | 0.77 | F10 (0.70) | F10PLAUPLGST14F2 | |
| SCHEMBL8202516 | 0.74 | ST14 (0.90) | F10PLAUPLGST14F2 | |
| SCHEMBL30583341 | 0.74 | F10 (1.00) | F10PLAUPLGST14F2 | |
| SCHEMBL18049396 | 0.73 | ST14 (1.00) | F10PLAUPLGST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013014074-A1 | USE OF TMPRSS2 INHIBITORS AS MEDICAMENTS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2013-01-31 | — | — | WO | disclosed |