SCHEMBL14669791

SCHEMBL14669791

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nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 7/20 0.51
▸ NMT2 O60551 6/20 0.51
▸ TLR2 O60603 1/20 0.40
▸ FOLH1 Q04609 1/20 0.40
▸ FURIN P09958 1/20 0.39
▸ CPB2 Q96IY4 2/20 0.38
▸ SIRT6 Q8N6T7 1/20 0.38
▸ SIRT1 Q96EB6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14669744 0.91 NMT2 (0.50) NMT1NMT2FURINSIRT6SIRT1
SCHEMBL29630443 0.87 NMT1 (0.51) NMT1NMT2TLR2FOLH1CPB2
SCHEMBL14669796 0.85 NMT2 (0.38) NMT1NMT2FOLH1FURINCPB2
SCHEMBL20529374 0.85 NMT2 (0.43) NMT1NMT2FOLH1FURINCPB2
SCHEMBL29591503 0.85 NMT1 (0.49) NMT1NMT2TLR2FOLH1FURIN
SCHEMBL30436706 0.85 NMT1 (0.52) NMT1NMT2TLR2FOLH1FURIN
SCHEMBL30781971 0.84 NMT1 (0.48) NMT1NMT2TLR2FOLH1FURIN
SCHEMBL31408939 0.84 GSR (0.47) NMT1NMT2FOLH1FURINCPB2
SCHEMBL31188429 0.84 GSR (0.47) NMT1NMT2TLR2FOLH1CPB2
SCHEMBL29564895 0.84 SLC15A2 (0.49) NMT1NMT2FOLH1FURINCPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130029920-A1 Metal Nanoparticles BRIMBLE MARGARET A (NZ) 2013-01-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130029920-A1 Metal Nanoparticles PSTPIP2, PCNP, ANPEP NMT1 395/4885NMT2 613/4885TLR2 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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