Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.59 |
| ▸ | ULK1 | O75385 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738468 | 0.86 | IGF1R (0.65) | IGF1R | |
| SCHEMBL14670395 | 0.81 | IGF1R (0.60) | IGF1R | |
| SCHEMBL12846048 | 0.76 | IGF1R (0.62) | IGF1R | |
| SCHEMBL14722578 | 0.76 | IGF1R (0.47) | IGF1RULK1 | |
| SCHEMBL15840798 | 0.76 | IGF1R (0.67) | IGF1R | |
| SCHEMBL14670388 | 0.74 | NEK1 (0.62) | IGF1R | |
| SCHEMBL4737845 | 0.73 | NTRK1 (0.71) | IGF1R | |
| SCHEMBL27738466 | 0.73 | NTRK1 (0.71) | IGF1R | |
| SCHEMBL18649472 | 0.70 | IGF1R (0.63) | IGF1R | |
| SCHEMBL22327886 | 0.69 | IGF1R (0.57) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013014162-A1 | HETEROCYCLYL PYRIMIDINE ANALOGUES AS JAK INHIBITORS | CELLZOME LIMITED (GB) | 2013-01-31 | — | — | WO | disclosed |