Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14670596 | 0.86 | IGF1R (0.59) | IGF1R | |
| SCHEMBL14670395 | 0.77 | IGF1R (0.60) | IGF1R | |
| SCHEMBL12846048 | 0.76 | IGF1R (0.62) | IGF1R | |
| SCHEMBL15840798 | 0.76 | IGF1R (0.67) | IGF1R | |
| SCHEMBL22327886 | 0.75 | IGF1R (0.57) | IGF1R | |
| SCHEMBL3006826 | 0.74 | IGF1R (0.56) | IGF1R | |
| SCHEMBL4737845 | 0.73 | NTRK1 (0.71) | IGF1R | |
| SCHEMBL27738466 | 0.73 | NTRK1 (0.71) | IGF1R | |
| SCHEMBL14723068 | 0.72 | IGF1R (0.49) | IGF1R | |
| SCHEMBL31268282 | 0.71 | IGF1R (0.54) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101218229-A | Pyrazolyl-amino-substituted pyrimidines and their use in the treatment of cancer | ASTRAZENECA AB (SE) | 2008-07-09 | — | — | CN | disclosed |