⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110068 | 0.71 | — | — | |
| SCHEMBL21827323 | 0.69 | — | — | |
| SCHEMBL318964 | 0.68 | — | — | |
| SCHEMBL2323196 | 0.67 | — | — | |
| SCHEMBL30045130 | 0.67 | CYP1A2 (0.35) | — | |
| SCHEMBL19546235 | 0.67 | CYP1A2 (0.35) | — | |
| SCHEMBL1819677 | 0.67 | — | — | |
| SCHEMBL2318535 | 0.66 | DRD2 (0.39) | — | |
| SCHEMBL1069 | 0.62 | — | — | |
| SCHEMBL151183 | 0.62 | CYP1A2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2996692-B1 | MEANS AND METHODS FOR TREATING CANCER | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2021-06-30 | — | — | EP | claimed |
| US-20160074391-A1 | MEANS AND METHODS FOR TREATING CANCER | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2016-03-17 | — | — | US | claimed |
| US-RE42353-E1 | Quinazoline derivatives and pharmaceutical compositions containing them | ASTRAZENECA UK LIMITED (GB) | 2011-05-10 | — | — | US | claimed |
| US-20090233926-A1 | 2-BENZIMIDAZOLYL-6-MORPHOLINO-4-PIPERIDIN-4-YLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA (SE) | 2009-09-17 | — | — | US | claimed |
| US-20090227586-A1 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-10 | — | — | US | claimed |
| EP-2054392-A2 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES AS INHIBITORS OF PROTEIN KINASE C-ALPHA | Boehringer Ingelheim International GmbH (DE) | 2009-05-06 | — | — | EP | claimed |
| US-7456281-B2 | Nucleic acid melting analysis with saturation dyes | IDAHO TECHNOLOGY, INC. | 2008-11-25 | — | — | US | claimed |
| JP-2008510698-A | — | — | 2008-04-10 | — | — | JP | claimed |
| WO-2007146981-A2 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES AS INHIBITORS OF PROTEIN KINASE C-ALPHA | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-12-21 | — | — | WO | claimed |
| US-20070293494-A1 | 2-Anilino-4-(Heterocyclic) Amino-Pyrimidines | DJUNG JANE F | 2007-12-20 | — | — | US | claimed |
| EP-1774047-A2 | NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES | University of Utah Research Foundation (US) | 2007-04-18 | — | — | EP | claimed |
| US-20070020672-A1 | Nucleic acid melting analysis with saturation dyes | IDAHO TECHNOLOGY, INC. (US) | 2007-01-25 | — | — | US | claimed |
| WO-2006121423-A2 | NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2006-11-16 | — | — | WO | claimed |
| US-20050233335-A1 | standard PCR solution with additional saturating double-stranded (ds) DNA binding dye; fluorescence; cyanine dyes | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2005-10-20 | — | — | US | claimed |
| EP-0929530-B1 | QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2002-11-20 | — | — | EP | claimed |
| US-6414148-B1 | PRODUCE ANTIANGIOGENIC AND/OR VASCULAR PERMEABILITY REDUCING EFFECT IN WARM-BLOODED ANIMALS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | claimed |
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | claimed |
| EP-3927450-B1 | PROCESS FOR REMOVAL OF ACID GASES FROM A FLUID STREAM WITH A LIQUID ABSORBENT COMPRISING A PIPERAZINE RING | BASF SE (DE) | 2023-06-07 | — | — | EP | disclosed |
| EP-0049683-A2 | Imidazo-rifamycines, process for their preparation, pharmaceutical preparations containing them and their use | CIBA-GEIGY AG (CH) | 1982-04-14 | — | — | EP | disclosed |
| EP-0023885-A1 | Method for the introduction of an oxygen-containing functional group into ansamycines, compounds thus obtained, and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |