Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.60 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14676147 | 0.89 | HSD11B1 (0.62) | HSD11B1 | |
| SCHEMBL14675678 | 0.87 | HSD11B1 (0.57) | HSD11B1HSD11B2 | |
| SCHEMBL14676588 | 0.87 | HSD11B1 (0.73) | HSD11B1 | |
| SCHEMBL14676635 | 0.83 | HSD11B1 (0.72) | HSD11B1HSD11B2 | |
| SCHEMBL14675541 | 0.81 | HSD11B1 (0.74) | HSD11B1HSD11B2 | |
| SCHEMBL14676308 | 0.81 | HSD11B1 (0.55) | HSD11B1 | |
| SCHEMBL14676370 | 0.81 | HSD11B1 (0.72) | HSD11B1 | |
| SCHEMBL14676469 | 0.80 | HSD11B1 (0.74) | HSD11B1HSD11B2 | |
| SCHEMBL14675984 | 0.80 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL14676472 | 0.80 | HSD11B1 (0.59) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013019091-A2 | A COMPOUND FOR INHIBITING 11β-HYDROXY STEROID DEHYDROGENASE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2013-02-07 | — | — | WO | disclosed |