Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CCND3 | P30281 | 2/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825903 | 0.86 | KCNH2 (0.43) | KCNH2CCND3CDK6KARS1SMN1; SMN2 | |
| SCHEMBL2226024 | 0.85 | USP2 (0.51) | CTSCCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14673765 | 0.85 | ABL1 (0.39) | CTSCCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16519341 | 0.84 | FLT3 (0.37) | CCND3CDK6CCNKCDK9 | |
| SCHEMBL14673613 | 0.82 | KARS1 (0.41) | TRPV1KCNH2CCND3CDK6KARS1 | |
| SCHEMBL14673616 | 0.78 | KARS1 (0.52) | KARS1MAP3K12 | |
| SCHEMBL27899683 | 0.78 | CCNK (0.43) | CYP1A2CYP3A4CYP2D6CCND3CDK6 | |
| SCHEMBL2364512 | 0.78 | WEE1 (0.42) | FYN | |
| SCHEMBL2224952 | 0.77 | BPTF (0.41) | KCNH2KARS1SMN1; SMN2MAP3K12 | |
| SCHEMBL14673902 | 0.77 | JAK2 (0.52) | CCND3CDK6KARS1SMN1; SMN2CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962665-B2 | Thiazole and oxazole kinase inhibitors | AB SCIENCE (FR) | 2015-02-24 | — | — | US | disclosed |
| US-20130035331-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | AB SCIENCE (FR) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035331-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | SYK, LTK, MERTK | TRPV1 3207/4885CTSC 1309/4885CYP1A2 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.