SCHEMBL14683533

SCHEMBL14683533

CCC(=O)NCCOCCOCC(=O)NCCCC[C@H](C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.48
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ RECQL P46063 2/20 0.39
▸ TSHR P16473 1/20 0.37
▸ FAAH O00519 1/20 0.35
▸ ACE2 Q9BYF1 1/20 0.35
▸ LTA4H P09960 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24198474 1.00 GLP1R (0.48) GLP1RMEN1KMT2ARECQLTSHR
SCHEMBL71906 0.90 MEN1 (0.45) GLP1RMEN1KMT2ARECQLTSHR
SCHEMBL14683572 0.90 GLP1R (0.46) GLP1RMEN1KMT2ARECQLTSHR
SCHEMBL14683490 0.88 MEN1 (0.44) GLP1RMEN1KMT2ARECQLTSHR
SCHEMBL12424086 0.87 GLP1R (0.62) GLP1R
SCHEMBL24470266 0.86 GLP1R (0.48) GLP1RMEN1KMT2ARECQL
SCHEMBL12518540 0.85 GLP1R (0.60) GLP1R
SCHEMBL20900405 0.85 GLP1R (0.57) GLP1RFAAH
SCHEMBL21172359 0.85 GLP1R (0.49) GLP1RMEN1KMT2ARECQL
SCHEMBL19135688 0.85 GLP1R (0.59) GLP1RRECQLTSHRFAAHACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GIPR, IAPP GLP1R 1/4885MEN1 858/4885KMT2A 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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