SCHEMBL14685808

SCHEMBL14685808

CCCOCCOCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.56
▸ TLR2 O60603 1/20 0.39
▸ TSHR P16473 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ NOD1 Q9Y239 3/20 0.37
▸ GNPAT O15228 1/20 0.37
▸ C3AR1 Q16581 1/20 0.36
▸ FAAH O00519 1/20 0.36
▸ FOLH1 Q04609 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15507481 0.93 GLP1R (0.48) GLP1RTLR2TSHRRECQLNOD1
SCHEMBL15002878 0.90 GLP1R (0.51) GLP1RTLR2NOD1GNPATC3AR1
SCHEMBL15002872 0.90 GLP1R (0.51) GLP1RGNPATFOLH1
SCHEMBL29330865 0.89 GLP1R (0.57) GLP1RTLR2TSHRRECQLNOD1
SCHEMBL21172251 0.86 GLP1R (0.62) GLP1RNOD1C3AR1FOLH1
SCHEMBL24788148 0.85 GLP1R (0.50) GLP1RTSHRRECQLNOD1
SCHEMBL16948614 0.85 GLP1R (0.61) GLP1RNOD1GNPATFOLH1
SCHEMBL17131138 0.84 GLP1R (0.65) GLP1RNOD1GNPATC3AR1FOLH1
SCHEMBL15850010 0.84 GLP1R (0.60) GLP1RNOD1C3AR1FOLH1
SCHEMBL15850000 0.84 GLP1R (0.60) GLP1RNOD1C3AR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035285-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GIPR, IAPP GLP1R 1/4885TLR2 3724/4885TSHR 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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