SCHEMBL16948614

SCHEMBL16948614

NN[C@@H](CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.61
▸ FOLH1 Q04609 3/20 0.44
▸ GNPAT O15228 1/20 0.43
▸ NOD1 Q9Y239 1/20 0.40
▸ EPOR P19235 1/20 0.40
▸ EPHX2 P34913 3/20 0.38
▸ ITGB3 P05106 1/20 0.38
▸ ITGA2B P08514 1/20 0.38
▸ CCKAR P32238 2/20 0.37
▸ CCKBR P32239 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14114131 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL12806481 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL12806536 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL12296711 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL16948269 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL24486694 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL8248469 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL12296653 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL18573658 0.94 GLP1R (0.70) GLP1RFOLH1GNPATNOD1CCKAR
SCHEMBL17401206 0.93 GLP1R (0.69) GLP1RFOLH1GNPATNOD1CCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150210747-A1 PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES NOVO NORDISK AS (DK) 2015-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210747-A1 PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES IAPP, IDE, LIPE GLP1R 54/4885FOLH1 524/4885GNPAT 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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