Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505038 | 0.83 | PTPN1 (0.44) | PTPN1PTPN11PTPN2TYRCYP3A4 | |
| SCHEMBL19503247 | 0.82 | ALDH1A1 (0.45) | PTPN1PTPN11HMGCRALOX5MAPT | |
| SCHEMBL10933384 | 0.82 | HTT (0.42) | PTPN1PTPN11HMGCRALOX5HTT | |
| SCHEMBL11700695 | 0.82 | PTPN1 (0.44) | PTPN1PTPN11PTPN2HMGCRCYP3A4 | |
| SCHEMBL5702284 | 0.77 | PTPN1 (0.56) | PTPN1PTPN11PTPN2TYRHMGCR | |
| SCHEMBL1179417 | 0.77 | PTPN1 (0.56) | PTPN1PTPN11PTPN2TYRHMGCR | |
| SCHEMBL23628389 | 0.75 | PTPN1 (0.55) | PTPN1PTPN11PTPN2TYRHMGCR | |
| SCHEMBL9143138 | 0.75 | PTPN1 (0.55) | PTPN1PTPN11PTPN2TYRHMGCR | |
| SCHEMBL1760574 | 0.75 | PTPN1 (0.53) | PTPN1PTPN11PTPN2TYRHMGCR | |
| SCHEMBL28722613 | 0.75 | PTPN1 (0.53) | PTPN1PTPN11PTPN2TYRHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556816-A2 | Permanent hair dye in the form of foam | "Aroma" Plc. (BG) | 2013-02-13 | — | — | EP | disclosed |