Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 4/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3049059 | 0.99 | PTGDR (0.40) | PTGDRPTGDR2CCR2CCR1ITGB3 | |
| SCHEMBL14686183 | 0.92 | PTGDR (0.45) | PTGDRPTGDR2CCR2CCR1 | |
| Hydrochloric Acid SCHEMBL3051812 | 0.92 | PTGDR (0.44) | PTGDRPTGDR2CCR2CCR1 | |
| SCHEMBL14686142 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BKDM1A | |
| SCHEMBL15016271 | 0.88 | PTGDR (0.43) | PTGDRPTGDR2CCR2CCR1ITGB3 | |
| Hydrochloric Acid SCHEMBL3143528 | 0.87 | PTGDR (0.42) | PTGDRPTGDR2CCR2CCR1ITGB3 | |
| SCHEMBL15016227 | 0.87 | PTGDR (0.42) | PTGDRPTGDR2CCR2CCR1ITGB3 | |
| Hydrochloric Acid SCHEMBL3144060 | 0.86 | PTGDR (0.42) | PTGDRPTGDR2CCR2CCR1ITGB3 | |
| SCHEMBL15016291 | 0.86 | PTGDR (0.43) | PTGDRPTGDR2CCR2CCR1 | |
| SCHEMBL14686223 | 0.85 | PTGDR (0.46) | PTGDRPTGDR2CCR2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057116-B1 | NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-02-13 | — | — | EP | claimed |