Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 7/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3040716 | 0.99 | CXCR3 (0.39) | CXCR3KLKB1CHRM1SLC6A9SLC6A5 | |
| SCHEMBL14686207 | 0.95 | CXCR3 (0.41) | CXCR3KLKB1CHRM1USP5POLB | |
| SCHEMBL3046480 | 0.95 | CXCR3 (0.38) | CXCR3KLKB1CHRM1USP5POLB | |
| Hydrochloric Acid SCHEMBL3053536 | 0.94 | CXCR3 (0.41) | CXCR3KLKB1CHRM1USP5POLB | |
| SCHEMBL14686171 | 0.93 | CXCR3 (0.45) | CXCR3SLC6A9SLC6A5ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL3043975 | 0.92 | CXCR3 (0.44) | CXCR3SLC6A9SLC6A5ALDH1A1RAB9A | |
| SCHEMBL14686174 | 0.87 | CXCR3 (0.46) | CXCR3RAB9AUSP5POLBKDM1A | |
| Hydrochloric Acid SCHEMBL3047703 | 0.86 | CXCR3 (0.45) | CXCR3RAB9AUSP5POLBKDM1A | |
| SCHEMBL3048107 | 0.85 | KDM4E (0.49) | — | |
| SCHEMBL14686144 | 0.85 | CXCR3 (0.45) | CXCR3USP5POLBKDM1AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057116-B1 | NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-02-13 | — | — | EP | claimed |