Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18427309 | 0.90 | STING1 (0.46) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL18427349 | 0.90 | STING1 (0.46) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL5267159 | 0.90 | STING1 (0.46) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL30054526 | 0.85 | ABCB1 (0.47) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL30054293 | 0.85 | ABCB1 (0.47) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL31161069 | 0.84 | STING1 (0.44) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL31160647 | 0.84 | STING1 (0.44) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL31160649 | 0.84 | STING1 (0.44) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL10903512 | 0.83 | STING1 (0.46) | STING1MEN1MAPTKMT2AABCB1 | |
| SCHEMBL5524426 | 0.82 | STING1 (0.44) | STING1MEN1MAPTKMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187448-B2 | Flavonoid compounds | CARDERO THERAPEUTICS, INC. (US) | 2015-11-17 | — | — | US | disclosed |
| US-20140256741-A1 | FLAVONOID COMPOUNDS | CARDERO THERAPEUTICS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| EP-2739613-A2 | FLAVONOID COMPOUNDS | Cardero Therapeutics, Inc. (US) | 2014-06-11 | — | — | EP | disclosed |
| WO-2013022846-A2 | FLAVONOID COMPOUNDS | CARDERO THERAPEUTICS, INC. (US) | 2013-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256741-A1 | FLAVONOID COMPOUNDS | FIS1, TFAM, MFN2 | STING1 2452/4885MEN1 4747/4885MAPT 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.