Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549879 | 0.92 | GPR119 (0.66) | GPR119KCNH2 | |
| SCHEMBL1550711 | 0.92 | GPR119 (0.55) | GPR119KCNH2 | |
| SCHEMBL14693051 | 0.84 | GPR119 (0.57) | GPR119KCNH2 | |
| SCHEMBL1549861 | 0.82 | GPR119 (0.41) | GPR119 | |
| Hydrochloric Acid SCHEMBL1550640 | 0.81 | GPR119 (0.40) | GPR119 | |
| SCHEMBL1550713 | 0.79 | GPR119 (0.60) | GPR119 | |
| SCHEMBL12213566 | 0.78 | GPR119 (0.88) | GPR119KCNH2 | |
| SCHEMBL2540165 | 0.78 | GPR119 (0.57) | GPR119KCNH2 | |
| SCHEMBL1550301 | 0.77 | GPR119 (0.56) | GPR119KCNH2 | |
| SCHEMBL2540230 | 0.77 | GPR119 (0.66) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372837-B2 | Pyridone and pyridazone analogues as GPR119 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-02-12 | — | — | US | disclosed |