Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2547658 | 0.94 | GPR119 (0.67) | GPR119KCNH2 | |
| SCHEMBL14693051 | 0.89 | GPR119 (0.57) | GPR119KCNH2 | |
| SCHEMBL2540165 | 0.89 | GPR119 (0.57) | GPR119KCNH2 | |
| SCHEMBL2540230 | 0.89 | GPR119 (0.66) | GPR119KCNH2 | |
| SCHEMBL1550301 | 0.89 | GPR119 (0.56) | GPR119KCNH2 | |
| SCHEMBL1549931 | 0.87 | GPR119 (0.54) | GPR119KCNH2 | |
| SCHEMBL14693052 | 0.87 | GPR119 (0.55) | GPR119KCNH2 | |
| SCHEMBL14693055 | 0.87 | GPR119 (0.53) | GPR119KCNH2 | |
| SCHEMBL14693050 | 0.86 | GPR119 (0.50) | GPR119KCNH2 | |
| SCHEMBL2540894 | 0.80 | GPR119 (0.50) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372837-B2 | Pyridone and pyridazone analogues as GPR119 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-02-12 | — | — | US | disclosed |