Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400780 | 0.94 | ELANE (0.73) | ELANEKMT2ALMNAMEN1MAPT | |
| SCHEMBL15064112 | 0.86 | ELANE (0.86) | ELANEKMT2ALMNAMEN1MAPT | |
| SCHEMBL449938 | 0.86 | ELANE (0.59) | ELANEKMT2ALMNAMEN1MAPT | |
| SCHEMBL28282084 | 0.81 | ELANE (0.54) | ELANEKMT2ALMNAMEN1MAPT | |
| Butanedione SCHEMBL28306363 | 0.80 | ELANE (0.94) | ELANEKMT2ALMNAMEN1MAPT | |
| SCHEMBL144013 | 0.80 | ELANE (1.00) | ELANEKMT2AMEN1SRD5A2ATM | |
| SCHEMBL2404682 | 0.80 | ELANE (0.76) | ELANEKMT2ALMNAMEN1MAPT | |
| SCHEMBL15908309 | 0.80 | ELANE (0.76) | ELANEKMT2ALMNAMAPTSRD5A2 | |
| SCHEMBL18530461 | 0.80 | ELANE (0.81) | ELANEKMT2ASRD5A2ATM | |
| SCHEMBL19985115 | 0.80 | ELANE (0.76) | ELANEKMT2ALMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025443-A2 | RADIATION CURABLE PRESSURE SENSITIVE ADHESIVE SHEET | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-21 | — | — | WO | disclosed |