SCHEMBL15908309

SCHEMBL15908309

C=C(C)C(=O)Oc1ccc(C(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.76
LMNA P02545 2/20 0.58
ALDH1A1 P00352 1/20 0.55
KMT2A Q03164 1/20 0.49
ATM Q13315 1/20 0.49
SRD5A2 P31213 1/20 0.48
MAPT P10636 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644844 0.94 ELANE (0.88) ELANELMNAALDH1A1KMT2AATM
SCHEMBL15064112 0.93 ELANE (0.86) ELANELMNAKMT2AATMMAPT
SCHEMBL146180 0.91 LMNA (0.63) ELANELMNAALDH1A1KMT2AATM
SCHEMBL19393872 0.88 ELANE (0.59) ELANELMNAALDH1A1KMT2AATM
SCHEMBL12277346 0.86 ELANE (0.58) ELANELMNAALDH1A1KMT2AATM
SCHEMBL19985115 0.86 ELANE (0.76) ELANELMNAKMT2AATMSRD5A2
SCHEMBL2404682 0.86 ELANE (0.76) ELANELMNAALDH1A1KMT2AATM
SCHEMBL18530461 0.86 ELANE (0.81) ELANEKMT2AATMSRD5A2HSD17B10
SCHEMBL144013 0.86 ELANE (1.00) ELANEALDH1A1KMT2AATMSRD5A2
SCHEMBL13683846 0.86 LMNA (0.57) ELANELMNAALDH1A1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017030950-A1 PHOTOACTIVATABLE FOULING-RESISTANT COPOLYMERS ARROW INTERNATIONAL, INC. (US) 2017-02-23 WO disclosed
US-20140211140-A1 Alignment Film Material and Corresponding Liquid Crystal Panel SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2014-07-31 US disclosed