Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.61 |
| ▸ | FBP1 | P09467 | 6/20 | 0.58 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.55 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.48 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858645 | 0.89 | ANO1 (0.63) | ANO1FBP1FFAR2USP30KCNH2 | |
| SCHEMBL3777315 | 0.81 | KCNH2 (0.63) | ANO1FBP1FFAR2USP30KCNH2 | |
| SCHEMBL4920542 | 0.81 | CSNK1D (0.73) | ANO1FBP1FFAR2KCNH2CSNK1D | |
| SCHEMBL14047971 | 0.80 | FFAR2 (0.60) | ANO1FBP1FFAR2USP30KCNH2 | |
| SCHEMBL7431194 | 0.80 | ANO1 (0.54) | ANO1FBP1FFAR2USP30KCNH2 | |
| SCHEMBL4866482 | 0.77 | CSNK1D (0.52) | ANO1FBP1FFAR2USP30KCNH2 | |
| SCHEMBL18824198 | 0.77 | FFAR2 (0.59) | ANO1FBP1FFAR2KCNH2MEN1 | |
| SCHEMBL24349097 | 0.76 | ANO1 (1.00) | ANO1MEN1KMT2ATP53 | |
| SCHEMBL5550664 | 0.76 | ANO1 (0.73) | ANO1FFAR2MEN1KMT2ATP53 | |
| SCHEMBL8125417 | 0.76 | SCD (0.64) | ANO1FBP1FFAR2KCNH2CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10611733-B2 | Quinazolinone analogs and use of quinazolinone analogs for treating or preventing certain viral infections | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2020-04-07 | — | — | US | disclosed |
| US-20170144978-A1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | SOUTHERN RESEARCH INSTITUTE | 2017-05-25 | — | — | US | disclosed |
| US-9598402-B2 | Quinazolinone analogs and use of quinazolinone analogs for treating or preventing certain viral infections | SOUTHERN RESEARCH INSTITUTE (US) | 2017-03-21 | — | — | US | disclosed |
| EP-2744787-B1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | SOUTHERN RES INST (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20140256753-A1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2014-09-11 | — | — | US | disclosed |
| EP-2744787-A1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | Southern Research Institute (US) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013025508-A1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | SOUTHERN RESEARCH INSTITUTE (US) | 2013-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256753-A1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | HAVCR2, EIF2AK2, GLS2 | ANO1 4045/4885FBP1 242/4885FFAR2 4524/4885 |
| US-20170144978-A1 | QUINAZOLINONE ANALOGS AND USE OF QUINAZOLINONE ANALOGS FOR TREATING OR PREVENTING CERTAIN VIRAL INFECTIONS | ZC3HAV1, EIF2AK2, GTF3C3 | ANO1 4282/4885FBP1 303/4885FFAR2 4766/4885 |
| US-10611733-B2 | Quinazolinone analogs and use of quinazolinone analogs for treating or preventing certain viral infections | ZC3HAV1, EIF2AK2, GTF3C3 | ANO1 4282/4885FBP1 303/4885FFAR2 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.