SCHEMBL1469736

SCHEMBL1469736

CCCC/C=C/c1ccccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 1/20 0.41
CYSLTR2 Q9NS75 2/20 0.41
CYSLTR1 Q9Y271 2/20 0.41
BACE1 P56817 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
CYP1A2 P05177 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1469737 1.00 PDE5A (0.41) PDE5ACYSLTR2CYSLTR1BACE1HDAC8
SCHEMBL1469640 0.95 CYSLTR2 (0.46) CYSLTR2CYSLTR1HDAC8
SCHEMBL1469642 0.95 CYSLTR2 (0.46) CYSLTR2CYSLTR1HDAC8
SCHEMBL1469238 0.89 TLR8 (0.43) BACE1
SCHEMBL1469236 0.89 TLR8 (0.43) BACE1
SCHEMBL6041126 0.82 SOAT1 (0.39) BACE1HDAC8
SCHEMBL1471407 0.82 BACE1 (0.43) BACE1
SCHEMBL1024642 0.82 BACE1 (0.43) BACE1
2-Phenylphenol SCHEMBL28192981 0.79 BCL2L1 (0.46) CYSLTR2CYSLTR1
SCHEMBL11122102 0.79 TOP1 (0.50) CYSLTR2CYSLTR1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2202832-B1 SOLID POLYMER ELECTROLYTE MEMBRANE, METHOD FOR PRODUCING THE SAME, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL SHINETSU CHEMICAL CO (JP) 2011-11-02 EP disclosed
US-20110070523-A1 SOLID POLYMER ELECTROLYTE MEMBRANE, METHOD FOR PRODUCING THE SAME, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-03-24 US disclosed
EP-2202832-A1 SOLID POLYMER ELECTROLYTE MEMBRANE, METHOD FOR PRODUCING THE SAME, MEMBRANE-ELECTRODE ASSEMBLY FOR FUEL CELL, AND FUEL CELL Shin-Etsu Chemical Co., Ltd. (JP) 2010-06-30 EP disclosed
EP-0180771-B1 METHOD FOR IMPROVING IMPULSE BREAKDOWN STRENGTH OF ELECTRICALLY INSULATING MATERIALS Nippon Petrochemicals Co., Ltd. (JP) 1989-08-02 EP disclosed