Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 6/20 | 0.41 |
| ▸ | THRA | P10827 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336193 | 0.89 | TDP1 (0.52) | ALDH1A1USP2HPGDTDP1HDAC1 | |
| SCHEMBL12989712 | 0.89 | TDP1 (0.52) | ALDH1A1USP2HPGDTDP1HDAC1 | |
| SCHEMBL11328438 | 0.87 | TDP1 (0.48) | ALDH1A1USP2HPGDTDP1HDAC1 | |
| SCHEMBL3112000 | 0.84 | ESR1 (0.57) | ALDH1A1USP2HPGDTDP1TRPV1 | |
| SCHEMBL3095896 | 0.84 | ESR1 (0.57) | ALDH1A1USP2HPGDTDP1TRPV1 | |
| SCHEMBL3091017 | 0.84 | ESR1 (0.57) | ALDH1A1USP2HPGDTDP1TRPV1 | |
| SCHEMBL3113234 | 0.84 | ESR1 (0.57) | ALDH1A1USP2HPGDTDP1TRPV1 | |
| SCHEMBL10982835 | 0.83 | CHKA (0.41) | ALDH1A1HPGDTHRBMEN1KMT2A | |
| SCHEMBL3100617 | 0.82 | ESR1 (0.53) | ALDH1A1TRPV1ESR1ADRA2AADORA3 | |
| SCHEMBL3290855 | 0.82 | TDP1 (0.46) | ALDH1A1USP2HPGDTDP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110070659-A1 | SAMPLE PRESENTATION DEVICE | QIAGEN SCIENCES, INC. (DE) | 2011-03-24 | — | — | US | disclosed |
| US-20080248589-A1 | Sample Presentation Device | LUMICYTE, INC. | 2008-10-09 | — | — | US | disclosed |
| EP-1756543-A2 | SAMPLE PRESENTATION DEVICE | Qiagen Sciences, Inc. (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1656202-A1 | SAMPLE PRESENTATION DEVICE WITH DIFFERING WETTABILITY | Qiagen Sciences, Inc. (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005114132-A2 | SAMPLE PRESENTATION DEVICE | QIAGEN SCIENCES, INC. (DE) | 2005-12-01 | — | — | WO | disclosed |
| US-20050164402-A1 | Sample presentation device | QLAGEN SCIENCES, INC. (DE) | 2005-07-28 | — | — | US | disclosed |
| WO-2005016530-A1 | SAMPLE PRESENTATION DEVICE WITH DIFFERING WETTABILITY | QIAGEN SCIENCES, INC. (DE) | 2005-02-24 | — | — | WO | disclosed |