Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.47 |
| ▸ | F2R | P25116 | 14/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14698321 | 0.86 | HPGD (0.45) | ITGB3ITGA2BF2RALDH1A1MEN1 | |
| SCHEMBL14635912 | 0.84 | HTT (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL23883116 | 0.81 | ALDH1A1 (0.60) | ITGB3ITGA2BF2RALDH1A1MEN1 | |
| SCHEMBL23883115 | 0.81 | ALDH1A1 (0.60) | ITGB3ITGA2BF2RALDH1A1MEN1 | |
| SCHEMBL25453024 | 0.71 | MEN1 (0.57) | ITGB3ITGA2BF2RALDH1A1MEN1 | |
| SCHEMBL23424118 | 0.70 | CHRM2 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL15492415 | 0.70 | CHRM2 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL18685665 | 0.70 | CHRM2 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL15247085 | 0.70 | CHRM2 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL19404105 | 0.70 | CHRM2 (0.41) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105221-A1 | METAL CHELATE COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA | Bayer Pharma Aktiengesellschaft (DE) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015121163-A1 | METAL CHELATE COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-08-20 | — | — | WO | disclosed |
| EP-2744802-A1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI | Piramal Imaging SA (CH) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013023795-A1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI | PIRAMAL IMAGING SA (CH) | 2013-02-21 | — | — | WO | disclosed |