Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645036 | 0.80 | CDK5 (0.44) | ADRA2AADRA2BADRA2CIDO1ALDH1A1 | |
| SCHEMBL17984845 | 0.78 | CYP3A4 (0.46) | NPC1MPLMAP4K1IDO1SMN1; SMN2 | |
| SCHEMBL29648993 | 0.78 | ADRA2A (0.50) | NPC1ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL3310894 | 0.75 | MEN1 (0.45) | NPC1ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL1385607 | 0.74 | NPC1 (0.38) | NPC1MPLIDO1ALDH1A1LMNA | |
| SCHEMBL1383964 | 0.74 | NPC1 (0.38) | NPC1MPLIDO1ALDH1A1LMNA | |
| SCHEMBL31598494 | 0.74 | MEN1 (0.44) | NPC1ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL3869454 | 0.72 | KMT2A (0.41) | NPC1ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL20341749 | 0.72 | KDM1A (0.45) | NPC1ALDH1A1MAPT | |
| SCHEMBL17984846 | 0.71 | MEN1 (0.54) | NPC1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040704-B2 | Fluorescent dyes with large stokes shifts | UTI LIMITED PARTNERSHIP (CA) | 2015-05-26 | — | — | US | disclosed |
| US-20140206870-A1 | FLUORSCENT DYES WITH LARGE STOKES SHIFTS | UTI LIMITED PARTNERSHIP (CA) | 2014-07-24 | — | — | US | disclosed |
| WO-2013023292-A1 | FLUORESCENT DYES WITH LARGE STOKES SHIFTS | UTI LIMITED PARTNERSHIP (CA) | 2013-02-21 | — | — | WO | disclosed |