Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 4/20 | 0.51 |
| ▸ | EPOR | P19235 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14699489 | 1.00 | KMT2A (0.55) | KMT2ASMN1; SMN2LTA4HEPORALOX5 | |
| SCHEMBL16178662 | 0.86 | KMT2A (0.47) | KMT2ASMN1; SMN2LTA4HEPORALOX5 | |
| SCHEMBL16178663 | 0.86 | KMT2A (0.47) | KMT2ASMN1; SMN2LTA4HEPORALOX5 | |
| SCHEMBL14699537 | 0.85 | KMT2A (0.47) | KMT2ASMN1; SMN2LTA4HEPORALOX5 | |
| SCHEMBL14699539 | 0.85 | KMT2A (0.47) | KMT2ASMN1; SMN2LTA4HEPORALOX5 | |
| SCHEMBL14699538 | 0.83 | KMT2A (0.46) | KMT2ASMN1; SMN2LTA4HEPORALOX5 | |
| SCHEMBL16188945 | 0.82 | KMT2A (0.44) | KMT2ASMN1; SMN2LTA4HEPORALOX5 | |
| SCHEMBL3609023 | 0.81 | KMT2A (0.64) | KMT2ASMN1; SMN2LTA4HEPORALOX5 | |
| SCHEMBL28115743 | 0.81 | KMT2A (0.67) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 | |
| SCHEMBL28115744 | 0.81 | KMT2A (0.67) | KMT2ASMN1; SMN2ALOX5MAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744252-B2 | Compounds for binding to the platelet specific glycoprotein IIb/IIIa and their use for imaging of thrombi | PIRAMAL IMAGING SA (CH) | 2017-08-29 | — | — | US | disclosed |
| EP-2744802-B1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI | PIRAMAL IMAGING SA (CH) | 2017-01-04 | — | — | EP | disclosed |
| US-9345793-B2 | Compounds for binding to the platelet specific glycoprotein IIB/IIIA and their use for imaging of thrombi | PIRAMAL IMAGING SA (CH) | 2016-05-24 | — | — | US | disclosed |
| US-20160137629-A1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIb/IIIa AND THEIR USE FOR IMAGING OF THROMBI | PIRAMAL IMAGING SA (CH) | 2016-05-19 | — | — | US | disclosed |
| US-20140314669-A1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI | PIRAMAL IMAGING SA (CH) | 2014-10-23 | — | — | US | disclosed |
| EP-2744802-A1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI | Piramal Imaging SA (CH) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013023795-A1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI | PIRAMAL IMAGING SA (CH) | 2013-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140314669-A1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI | F13B, FGB, SELPLG | KMT2A 4576/4885SMN1; SMN2 4795/4885LTA4H 1100/4885 |
| US-20160137629-A1 | COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIb/IIIa AND THEIR USE FOR IMAGING OF THROMBI | F13B, FGB, SELPLG | KMT2A 4576/4885SMN1; SMN2 4795/4885LTA4H 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.