SCHEMBL14700032

SCHEMBL14700032

CCC1CCC(C2CCC(c3ccc(C)c(N)c3F)CC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 8/20 0.35
ALOX5AP P20292 2/20 0.32
FEN1 P39748 2/20 0.32
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5847812 0.87 OPRL1 (0.36) OPRL1NOTUM
SCHEMBL12140867 0.87 OPRL1 (0.36) OPRL1NOTUM
SCHEMBL14700017 0.84 OPRL1 (0.33) OPRL1
SCHEMBL14700026 0.84 OPRL1 (0.36) OPRL1ALOX5APFEN1NOTUM
SCHEMBL13235237 0.83 OPRL1 (0.34) OPRL1
SCHEMBL20888537 0.83 OPRL1 (0.34) OPRL1
SCHEMBL12716502 0.82 OPRL1 (0.39) OPRL1ALOX5APFEN1NOTUM
SCHEMBL13110472 0.80 OPRL1 (0.36) OPRL1
SCHEMBL5837243 0.79 TRPV3 (0.36) OPRL1
SCHEMBL5837247 0.79 TRPV3 (0.36) OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1873134-B1 CHLOROFLUOROBENZENE LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2013-02-13 EP disclosed