Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12602992 | 0.74 | CHRNA7 (0.41) | PDE2ATSHRCA2CA1CA5A | |
| SCHEMBL30949389 | 0.72 | CHRNA7 (0.42) | TSHRCA2CA1CA9CHRNA7 | |
| SCHEMBL25160357 | 0.69 | AKR1C3 (0.41) | KEAP1NFE2L2CHRNA7AKR1C3AKR1C2 | |
| SCHEMBL2680513 | 0.69 | PDE2A (0.47) | PDE2ATSHRCA2CA1CA5A | |
| SCHEMBL17086708 | 0.69 | ALDH1A1 (0.39) | TSHRCA2CHRNA7AKR1C3AKR1C2 | |
| SCHEMBL20706326 | 0.69 | CHRNA7 (0.39) | PDE2ATSHRCA2CA1CA9 | |
| SCHEMBL17399520 | 0.69 | ALDH1A1 (0.39) | TSHRCA2CHRNA7AKR1C3AKR1C2 | |
| SCHEMBL17086707 | 0.69 | ALDH1A1 (0.39) | TSHRCA2CHRNA7AKR1C3AKR1C2 | |
| SCHEMBL14438866 | 0.68 | TSHR (0.55) | PDE2ATSHRMLYCDCA2CA1 | |
| SCHEMBL25012720 | 0.68 | TSHR (0.55) | PDE2ATSHRMLYCDCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046862-B1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | CA NAT RESEARCH COUNCIL (CA) | 2013-02-13 | — | — | EP | disclosed |